Table 1.
Demographic, clinical and laboratory variables according to the group
| Variable | NT (n = 11) | PI (n = 24) | NNRTI (n = 33) | Control (n = 30) | Kruskal-Wallis test (p) | |
|---|---|---|---|---|---|---|
| Age (years) | M ± DP | 33.3 ± 4.1 | 44.8 ± 8.7 | 39.4 ± 8.0 | 49.9 ± 11.6 | < 0.001 |
| Md ± IQR | 33.0 ± 3.0 | 43.0 ± 10.5 | 39.0 ± 8.0 | 48.5 ± 15.0 | ||
| Gender | Male | 9 (81.8%) | 15 (62.5%) | 14 (42.4%) | 22 (73.3%) | 0.033 (chi-square) |
| Female | 2 (18.2%) | 9 (37.5%) | 19 (57.6%) | 8 (26.7%) | ||
| Md ± IQR | ||||||
| Heart rate (bpm) | M ± SD | 75.6 ± 7.3 | 72.0 ± 8.9 | 78.1 ± 6.2 | 73.2 ± 6.1 | 0.029 |
| Md ± IQR | 78.0 ± 14.0 | 73.5 ± 16.0 | 77.0 ± 9.5 | 75.0 ± 8.8 | ||
| SBP (mmHg) | M ± SD | 121.4 ± 6.0 | 129.3 ± 6.8 | 129.1 ± 6.8 | 123.8 ± 5.5 | 0.001 |
| Md ± IQR | 120.0 ± 5.0 | 130.0 ± 10.0 | 130.0 ± 5.0 | 125.0 ± 10.0 | ||
| DBP (mmHg) | M ± SD | 71.4 ± 4.5 | 70.0 ± 7.7 | 70.3 ± 7.5 | 67.8 ± 5.7 | 0.338 |
| Md ± IQR | 70.0 ± 5.0 | 70.0 ± 20.0 | 70.0 ± 15.0 | 70.0 ± 5.0 | ||
| Blood glucose (mg/dl) | M ± SD | 84.8 ± 14.2 | 79.7 ± 11.2 | 83.0 ± 9.5 | 82.4 ± 5.7 | 0.455 |
| Md ± IQR | 82.0 ± 23.0 | 79.0 ± 9.0 | 81.0 ± 13.5 | 81.0 ± 7.0 | ||
| Total cholesterol (mg/dL) | M ± SD | 164.6 ± 26.8 | 189.0 ± 56.3 | 183.9 ± 30.0 | 196.3 ± 17.4 | 0.021 |
| Md ± IQR | 163.0 ± 40.0 | 198.0 ± 54.0 | 181.0 ± 42.0 | 199.0 ± 26.0 | ||
| LDL-c (mg/dL) | M ± SD | 102.6 ± 27.6 | 108.7 ± 48.5 | 110.0 ± 27.9 | 118.9 ± 18.5 | 0.229 |
| Md ± IQR | 104.0 ± 49.0 | 109.0 ± 66.0 | 102.0 ± 36.0 | 122.0 ± 27.0 | ||
| HDL-c (mg/dL) | M ± SD | 47.5 ± 16.7 | 42.6 ± 17.5 | 55.0 ± 16.0 | 53.4 ± 3.5 | 0.007 |
| Md ± IQR | 43.0 ± 30.0 | 41.0 ± 22.0 | 52.0 ± 18.0 | 54.0 ± 4.0 | ||
| Triglycerides (mg/dL) | M ± SD | 101.1 ± 39.1 | 174.8 ± 78.2 | 119.7 ± 115.2 | 127.0 ± 15.5 | < 0.001 |
| Md ± IQR | 86.0 ± 79.0 | 165.0 ± 106.0 | 87.0 ± 71.0 | 123.5 ± 27.0 | ||
| CD4+ lymphocytes/mm3 | M ± SD | 502.5 ± 206.3 | 534.4 ± 323.1 | 693.2 ± 317.7 | - | 0.044 |
| Md ± IQR | 426.0 ± 310.0 | 404.0 ± 436.0 | 644.0 ± 297.0 | - |
M: mean; SD: standard deviation; Md: median; IQR: interquartile range; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; NT: HIV-positive patients not using antiretroviral therapy. PI: HIV-positive patients on protease inhibitor therapy. NNRTI: HIV-positive patients on non-nucleoside reverse transcriptase inhibitor therapy. Control: healthy HIV-negative individuals.