Table 2.
Echocardiographic variables
| Variable | NT (n = 11) | PI (n = 24) | NNRTI (n = 33) | Control (n = 30) | Kruskal-Wallis test (p) | |
|---|---|---|---|---|---|---|
| Aorta (mm) | M ± SD | 28.27 ± 1.85 | 30.58 ± 3.02 | 28.73 ± 2.97 | 29.53 ± 2.08 | 0.026 |
| Md ± IQR | 29.00 ± 3.00 | 30.00 ± 3.50 | 29.00 ± 4.00 | 30.00 ± 2.00 | ||
| LA diameter (mm) | M ± SD | 31.18 ± 3.82 | 33.21 ± 3.22 | 31.64 ± 4.59 | 34.33 ± 2.55 | 0.004 |
| Md ± IQR | 30.00 ± 6.00 | 32.00 ± 4.50 | 31.00 ± 3.00 | 34.00 ± 4.00 | ||
| LVDd-i (mm/m2) | M ± SD | 29.75 ± 0.79 | 29.75 ± 1.81 | 28.67 ± 2.36 | 28.20 ± 1.73 | 0.020 |
| Md ± IQR | 29.70 ± 1.13 | 29.87 ± 2.75 | 29.73 ± 4.22 | 28.65 ± 2.84 | ||
| LVSD (mm) | M ± SD | 30.36 ± 2.38 | 31.17 ± 4.04 | 32.18 ± 3.26 | 32.17 ± 2.78 | 0.248 |
| Md ± IQR | 30.00 ± 5.00 | 31.00 ± 7.00 | 32.00 ± 4.00 | 31.50 ± 4.00 | ||
| IVS (mm) | M ± SD | 7.18 ± 0.98 | 7.88 ± 1.08 | 7.91 ± 0.95 | 9.03 ± 0.76 | < 0.001 |
| Md ± IQR | 7.00 ± 2.00 | 8.00 ± 2.00 | 8.00 ± 2.00 | 9.00 ± 2.00 | ||
| PP (mm) | M ± SD | 7.00 ± 1.00 | 7.42 ± 1.18 | 7.67 ± 0.92 | 8.33 ± 0.80 | < 0.001 |
| Md ± IQR | 7.00 ± 0.00 | 8.00 ± 1.00 | 8.00 ± 1.00 | 9.00 ± 1.00 | ||
| LVEF – Simpson (%) | M ± SD | 66.64 ± 3.83 | 62.46 ± 3.60 | 63.55 ± 4.10 | 64.17 ± 3.50 | 0.030 |
| Md ± IQR | 67.00 ± 5.00 | 62.00 ± 5.00 | 63.00 ± 6.00 | 64.00 ± 6.00 | ||
| LV mass index (g/m2) | M ± SD | 82.23 ± 16.76 | 104.49 ± 24.01 | 90.01 ± 19.54 | 108.12 ± 14.25 | < 0.001 |
| Md ± IQR | 82.28 ± 13.59 | 106.35 ± 37.69 | 89.34 ± 26.89 | 110.61 ± 18.10 | ||
| E/A ratio | M ± SD | 1.46 ± 0.40 | 1.33 ± 0.34 | 1.52 ± 0.41 | 1.18 ± 0.07 | < 0.001 |
| Md ± IQR | 1.34 ± 0.38 | 1.30 ± 0.22 | 1.50 ± 0.44 | 1.18 ± 0.09 | ||
| E’ septal annulus (cm/s) | M ± SD | 9.55 ± 1.87 | 9.03 ± 1.91 | 10.54 ± 2.21 | 8.38 ± 0.41 | < 0.001 |
| Md ± IQR | 9.00 ± 1.90 | 8.35 ± 2.00 | 10.00 ± 3.00 | 8.15 ± 0.60 | ||
| S’ septal annulus (cm/s) | M ± SD | 8.25 ± 1.09 | 8.10 ± 0.68 | 8.49 ± 1.41 | 9.03 ± 0.95 | 0.001 |
| Md ± IQR | 8.00 ± 2.00 | 8.00 ± 0.40 | 8.10 ± 1.00 | 8.80 ± 0.60 | ||
| E/E’ ratio | M ± SD | 8.41 ± 1.33 | 8.72 ± 2.03 | 7.08 ± 1.65 | 9.29 ± 0.62 | < 0.001 |
| Md ± IQR | 8.40 ± 2.59 | 9.08 ± 3.04 | 7.27 ± 2.45 | 9.38 ± 0.88 | ||
| LA volume index (ml/m²) | M ± SD | 30.38 ± 6.16 | 29.93 ± 4.76 | 29.48 ± 5.60 | 29.56 ± 1.81 | 0.839 |
| Md ± IQR | 29.11 ± 1.09 | 30.40 ± 3.48 | 29.17 ± 7.32 | 29.88 ± 2.76 | ||
| S lateral tricuspid annulus (cm/s) | M ± SD | 11.29 ± 1.54 | 10.87 ± 1.42 | 12.23 ± 1.90 | 11.49 ± 0.90 | 0.014 |
| Md ± IQR | 11.00 ± 2.00 | 10.80 ± 2.00 | 12.00 ± 2.00 | 11.70 ± 0.50 |
M: mean; SD: standard deviation; Md: median; IQR: interquartile range; ST: HIV+ patient not using antiretroviral therapy. PI: HIV-positive patients on protease inhibitor therapy; NNRTI: HIV-positive patients on non-nucleoside reverse transcriptase inhibitor therapy. LVDD: left ventricular diastolic diameter; LVSD: left ventricular systolic diameter; ΔD%: left ventricle; LA: left atrium