Fig. 1. Schematic representation of single molecule monitoring of three types of Aβ1–42 peptides with glass nanopore sensors. Aβ1–42 monomers (a, green), oligomers (b, purple) and fibres (c, orange) could be distinguished in real time through the characteristic current fluctuations. The baseline currents in the nanopore sensing of Aβ1–42 monomers, oligomers and fibres are approximately –950 pA, –1670 pA and –1040 pA, which are obtained through three independent nanopores.
