Fig. 3. Aβ1–42 oligomer sensing with glass nanopores. (a) The typical step like current fluctuations induced by the adsorption of Aβ1–42 oligomers onto the nanopore sidewall. (b) Frequencies of the pulse-like signals for the sensing of three types of Aβ1–42 peptides. I–V curves of the glass nanopore measured in the pure electrolyte before (gray) and after Aβ1–42 monomer (c), oligomer (d) and fibre (e) sensing, respectively.