Table 5.
Factors affecting PFS and OS by multivariate Cox’s proportional hazards regression model analysis with Forward Stepwise (Conditional LR) method
| Parameters | Multivariate Cox’s regression | |||
|---|---|---|---|---|
| P-value | HR | 95% CI | ||
| Lower | Higher | |||
| PFS | ||||
| Largest nodule size ≥7 cm | 0.029 | 1.853 | 1.065 | 3.224 |
| ALB abnormal | 0.046 | 7.943 | 1.041 | 60.603 |
| OS | ||||
| CSM-TACE vs cTACE | 0.023 | 0.475 | 0.249 | 0.905 |
| Child-pugh stage (B/C vs A) | 0.036 | 2.020 | 1.046 | 3.899 |
| ALB abnormal | 0.001 | 141.415 | 8.509 | 2350.163 |
| ALP abnormal | 0.008 | 2.356 | 1.254 | 4.423 |
| AFP abnormal | 0.005 | 3.090 | 1.401 | 6.816 |
Notes: Data was presented as P-value, HR and 95% CI. Factors affecting PFS and OS were determined by multivariate Cox’s proportional hazards regression analysis with Forward Stepwise (Conditional LR) method. All the 36 baseline characteristics were included in the multivariate logistic model analysis. P-value <0.05 was considered significant, and the significant results were shown in boldface.
Abbreviations: PFS, progression-free survival; OS, overall survival; CSM-TACE, transarterial chemoembolization with CalliSpheres® microspheres; cTACE, conventional transarterial chemo-embolization; ALB, albumin; AFP, alpha-fetoprotein.