TABLE 6.
Correlations between plasma cerebrospinal fluid cytokines and depressive symptomatology
| Variables | Antenatal atypical depression score | Postpartum IDS-SR score | ||
|---|---|---|---|---|
| Spearman’s rho | P value | Spearman’s rho | P value | |
| Plasma IL-6 | −0.05 | 0.598 | −0.11 | .288 |
| Plasma IL-8 | 0.18 | 0.054 | 0.01 | .909 |
| Plasma IL-10 | 0.11 | 0.240 | 0.22 | .037 |
| Plasma IL-12p70 | 0.20 | 0.031 | 0.14 | .197 |
| Plasma IL-17a | −0.01 | 0.961 | 0.15 | .161 |
| Plasma IL-18 | 0.11 | 0.234 | 0.02 | .836 |
| Plasma IL-23 | −0.04 | 0.689 | −0.18 | .085 |
| Plasma IFNα | −0.09 | 0.368 | −0.05 | .628 |
| Plasma IFNγ | 0.21 | 0.024 | 0.17 | .109 |
| Plasma TNFα | −0.06 | 0.501 | −0.05 | .673 |
| Plasma MCP-1 | 0.09 | 0.318 | 0.06 | .570 |
| CSF IL-1β | 0.08 | 0.390 | −0.04 | .724 |
| CSF IL-6 | −0.04 | 0.707 | 0.07 | .529 |
| CSF IL-8 | −0.02 | 0.797 | 0.05 | .672 |
| CSF IL-18 | −0.10 | 0.302 | 0.02 | .828 |
| CSF IL-23 | 0.06 | 0.545 | 0.01 | .924 |
| CSF IL-33 | −0.03 | 0.766 | 0.11 | .316 |
| CSF IFNγ | 0.01 | 0.960 | −0.05 | .621 |
| CSF TNFα | −0.03 | 0.787 | 0.18 | .086 |
| CSF MCP-1 | 0.01 | 0.926 | 0.04 | .678 |
CSF, cerebrospinal fluid; IDS-SR, Inventory of Depressive Symptomatology-Self-Report; IFN, interferon; IL, interleukin; MCP, monocyte chemotactic protein; TNF, tumor necrosis factor.