Figure 1.

Morphological evaluation of the liver of Wistar rats fed high-fat diets for six weeks. STD (standard diet): preserved hepatic tissue architecture with conserved vascular distribution. HLD (high-lard diet): preserved hepatic tissue architecture with mild and uniform hepatic steatosis (black arrows), mild inflammatory infiltrate (white arrows), and mild passive hyperemia (arrowheads). HL/HCD (high-lard and high-cholesterol diet): altered tissue architecture with moderate hepatic steatosis, fat microvesicles and macrovesicles (black arrows), and marked inflammatory infiltrate (white arrows). The bars indicate 100 µm at 100x magnification (left panel) and 20 µm at 400x magnification (right panel).