. 2019 Nov;113(5):896–902. doi: 10.5935/abc.20190149

Table 2.

Body and liver weight and biochemical parameters of Wistar rats after six weeks of treatment with standard and high-fat diets

Parameter	Diet
Parameter	STD	HLD	HL/HCD
Body weight (g)
Initial	249.05 ± 21.44^a	243.85 ± 15.09^a	242.35 ± 16.78^a
Final	499.58 ± 65.32^a	564.08 ± 39.73^a	508.58 ± 47.68^a
Gain	250.53 ± 48.40^b	320.23 ± 44.50^a	266.23 ± 38.21^a,b
Liver
Weight (g)	14.90 ± 2.33^b	15.92 ± 1.65^b	27.10 ± 5.94^a
Relative weight (g/100g body weight)	2.98 ± 0.24^b	2.82 ± 0.14^b	5.28 ± 0.80^a
Serum lipid profile (mg/dL)
TC	59.83 ± 15.99^b	64.58 ± 14.13^b	87.75 ± 8.54^a
LDL-c	4.23 ± 0.71^b	6.98 ± 2.09^b	23.63 ± 4.55^a
HDL-c	30.74 ± 4.11^a	34.42 ± 7.77^a	26.74 ± 4.23^a
non-HDL-c	29.09 ± 12.13^b	30.17 ± 10.84^b	61.01 ± 6.95^a
VLDL-c	10.68 ± 1.58^b	16.77 ± 4.58^a,b	18.52 ± 7.51^a
TG	53.42 ± 7.91^b	83.83 ± 22.90^a,b	92.58 ± 37.55^a
Liver enzymes (U/L)
ALT	48.72 ± 15.91^b	28.16 ± 6.00^b	210.30 ± 137.78^a
AST	154.67 ± 22.42^b	117.00 ± 29.84^b	300.63 ± 60.26^a

Data are expressed as mean ± standard deviation. a,bValues in the same row with different superscript letters are significantly different (Tukey test, p < 0.05). STD: standard diet; HLD: high-lard diet; HL/HCD: high-lard and high-cholesterol diet; Relative liver weight = (liver weight/body weight) x 100; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol; VLDL-c: very low-density lipoprotein cholesterol; TG: triacylglycerol; non-HDL-c: non-high-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase.