Table 4.
Effects of environmental enrichment or standard conditions on the activity of enzymes and biomarkers of oxidative damage in the left kidney
| SOD (U/mg ptn) | Catalase (U/mg ptn) | Carbonyl protein (nmol/mg ptn) | TBARS (nM/mg ptn) | |
|---|---|---|---|---|
| Sham-St (n = 7) | 14.1 ± 5.9 | 1.4 ± 0.5 | 24.9 ± 8.8 | 0.5 ± 0.19 |
| Sham-EE (n = 13) | 17.4 ± 8.7 | 1.5 ± 0.8 | 31.9 ± 11.9 | 0.4 ± 0.2 |
| 2K1C-St (n = 12) | 11.3 ± 2.2 | 0.1 ± 0.06a,b | 25.9 ± 9.3 | 0.7 ± 0.3 |
| 2K1C-EE (n = 8) | 23.5 ± 6.2c | 0.4 ± 0.2a,b | 30.1 ± 8.1 | 0.4 ± 0.19 |
represents a significant difference between groups when compared to Sham-St;
represents a significant difference between groups when compared to Sham-EE;
represents a significant difference between groups when compared to 2K1C-St.
Analysed by one-way ANOVA, followed by Newman Keuls post-test (p < 0.05). Data are expressed as the mean ± SD (n = 7-13 in each group). Sham-St: normotensive group exposed to standard condition; Sham-EE: normotensive group exposed to environmental enrichment; 2K1C-St: hypertensive group exposed to standard condition; 2K1C-EE: hypertensive group exposed to environmental enrichment. SOD: superoxide dismutase; TBARS: thiobarbituric acid-reactive substances.