Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of the binding mode for GSK1 (beige), GSK2 (salmon) and BRD5492 (gray) ligands. Top figure shows location of the ligands in αβ heterodimer and bottom insert shows different orientations of ligands in the binding pocket and adjustment of protein side chains upon ligand binding
