Table 3.

Comparison of kinetic parameters of CATs toward chloramphenicol (Cm)

Gene	Organism	K m for Cm (μM)	k cat (s−1)	k cat/K m (M−1 s−1)	Reference
Type A CAT
cat	Agrobacterium tumefaciens	20.5			39
cat	Clostridium perfringens	21.5			39
cat	Diplococcus pneumoniae	10.0			39
catI	Escherichia coli	11.5			39
catII	Escherichia coli	18.0			39
catIII	Escherichia coli	16.3			39
catII	Haemophilus parainfluenzae	17.5			39
cat	Proteus mirabilis	31.0			39
catI	Pseudomonas aeruginosa	94			4
catA	Staphylococcus aureus	2.6			40
catB	Staphylococcus aureus	2.7			40
catC	Staphylococcus aureus	2.5			39
catD	Staphylococcus aureus	2.7			40
catIII	Staphylococcus aureus	162	209	1.29 × 106	41
cat	Streptomyces acrimycini	16.6			39
cat	Streptococcus agalactiae	9.3			39
cat	Vibrio anguillarum	34.5	26	7.54 × 105	42
Type B CATa
catB1	Pseudomonas aeruginosa	140			4
catB3	Pseudomonas aeruginosa	156			4
catB5	Pseudomonas aeruginosa	136			4
catB7	Pseudomonas aeruginosa	812			4
catB9	VCA0300 (VcCAT) Vibrio cholerae	939	95	1.01 × 105	This work
catB	VV20610 (VvCAT) Vibrio vulnificus	913	78	8.54 × 104	This work
Type C CAT
catC	VFA0790 (AfCAT) Aliivibrio fisherii	659	31	4.70 × 104	This work
catC	Vibrio parahaemolyticus VPA‐67	145	5.6	3.86 × 104	2

^aType B CATs are sometimes referred to as xenobiotic acetyltransferases (XATs) in the literature.