Figure 1. EMMI system and hybrid assessment method.

a, body-uterus geometry generation. Body-uterus geometry (original geometry) was acquired from MRI images (Beige, body surface; light pink, complete uterine surface; blue dots, locations where electrodes were placed; dark pink, the region of uterine surface where electrodes were placed). b, Simulation of body surface potentials under different conditions. The body-uterus geometry and experimentally measured uterine potentials were used to generate original body surface potentials. Noise-contaminated body surface potentials were generated by adding signal noise to original body surface potentials. A computer-simulated deformed geometry, derived from the original body-uterus geometry, was combined with measured uterine potentials to generate geometry-deformed body surface potentials. The black star denotes deformation center. c. Reconstruction and comparison of uterine surface signals. The three types of body surface potentials and original body-uterus geometry were input into EMMI software to reconstruct uterine surface potentials, respectively. Then respective original, noise-contaminated, and geometry-deformed uterine electrograms and isochrone maps were derived and compared.