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(a) Plasmid structure comparison between blaNDM-1-harbouring pKp202_1 and the selected mutants. (b) The blaNDM-1 deletion in Kp202 selected mutants. Coloured arrows indicate ORFs, with purple, orange, green, red and blue arrows representing replication genes, mobile elements, plasmid transfer genes, the antimicrobial and heavy metal resistance gene, and plasmid backbone genes, respectively. Blue shading denotes regions of shared homology among different elements.
