Fig. 5. Motility of influenza is driven by NA activity. De Haan et al. partially blocked receptors on BLI sensors with viruses that had inactive NA and then exposed the sensors to a virus with active NA.16 One sensor (in blue) was protected with the NA inhibitor oseltamivir carboxylate (OC), one sensor (in red) was only locally blocked by the NA-inactive virus, and one sensor (in green) was left fully unprotected. After regeneration of the sensors, exposure to new virus showed that receptors were cleaved from all unprotected areas. Adapted from ref. 16 with permission from Public Library of Sciences, licensed under CC BY 4.0.
