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. 2020 Feb 14;15(2):e0228684. doi: 10.1371/journal.pone.0228684

Table 3. Multivariable logistic regression analysis between dyslipidemia and hyperuricemia.

Crude Model 1a Model 2b Model 3c Model 4d
case (n) OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value
Combined lipid profile 8,722
Total cholesterol (10 mg/dL) 1.064 1.040, 1.087 < 0.001 1.07 1.046, 1.096 < 0.001 1.053 1.029, 1.078 < 0.001 1.053 1.028, 1.079 < 0.001 1.05 1.023, 1.077 < 0.001
Triglyceride (10 mg/dL) 1.022 1.013, 1.031 < 0.001 1.018 1.009, 1.027 < 0.001 1.017 1.009, 1.025 < 0.001 1.017 1.009, 1.026 < 0.001 1.017 1.009, 1.026 < 0.001
HDL-C (10 mg/dL) 0.675 0.619, 0.737 < 0.001 0.728 0.666, 0.796 < 0.001 0.806 0.736, 0.883 < 0.001 0.804 0.729, 0.887 < 0.001 0.808 0.732, 0.892 < 0.001
Number of dyslipidemia components 8,722
0 5,612 1 1 1 1 1
1 1,712 2.389 2.000, 2.853 < 0.001 2.068 1.724, 2.479 < 0.001 1.747 1.446, 2.111 < 0.001 1.702 1.389, 2.085 < 0.001 1.686 1.376, 2.065 < 0.001
2 1,184 3.092 2.552, 3.746 < 0.001 2.933 2.394, 3.594 < 0.001 2.365 1.926, 2.902 < 0.001 2.194 1.751, 2.748 < 0.001 2.146 1.712, 2.690 < 0.001
3 or more 214 4.99 3.539, 7.038 < 0.001 4.228 3.009, 5.940 < 0.001 3.096 2.197, 4.364 < 0.001 2.903 2.024, 4.165 < 0.001 2.813 1.956, 4.046 < 0.001

OR, odds ratio; CI, confidence interval; BMI, body mass index; BUN, blood urea nitrogen; GFR, glomerular filtration rate; HTN, hypertension; DM, diabetes; HDL-C, high density lipoprotein cholesterol.

a Model 1: Adjusted for sex and age.

b Model 2: Adjusted for sex, age, and BMI.

c Model 3: Adjusted for age, sex, waist circumference, BMI, hemoglobin, BUN, GFR, HTN, DM, smoking, alcohol consumption, and regular exercise.

d Model 4: Adjusted for age, sex, waist circumference, BMI, hemoglobin, BUN, GFR, HTN, DM, smoking, alcohol consumption, regular exercise, and dyslipidemia medication.