Table 2. Phenotype and resistance patterns from respiratory culture from patients in the Stanford CF cohort.
Antibiotic resistance was assessed in clinical P. aeruginosa isolates cultured from the same sputum samples in which Pf phage status was assessed in our cohort. N = 28 Pf phage–negative samples and 20 Pf phage–positive samples. Comparison by Pearson’s χ2 test.
| P. aeruginosa + by qPCR | P | ||
|---|---|---|---|
| Pf phage − | Pf phage + | ||
| Mucoid strain | 58.3% | 85.71% | 0.03 |
| Ciprofloxacin | 12 (33%) | 6 (29%) | 0.71 |
| Tobramycin | 7 (19%) | 7 (33%) | 0.24 |
| Aztreonam | 5 (14%) | 7 (33%) | 0.0499 |
| Amikacin | 8 (22%) | 14 (67%) | 0.0009 |
| Cefepime | 7 (19%) | 8 (38%) | 0.12 |
| Ceftazidime | 7 (19%) | 5 (23%) | 0.70 |
| Meropenem | 4 (11%) | 10 (48%) | 0.002 |
| Piperacillin-tazobactam | 7 (19%) | 5 (24%) | 0.70 |