Table 1.
Small RNA-seq Profiling Followed by Enrichment Analysis of miRNAs in Stem/EEC Progenitors (Sox9-Low, n = 3) and in Mature EECs (Sox9-High, n = 3) Relative to Unsorted Intestinal Epithelial Cells (n = 2)
| Class A miRNAs enriched in mature EEC (Sox9-High) |
Class B miRNAs enriched in progenitor EEC (Sox9-Low) |
Class C miRNAs enriched in both mature and progenitor EECs |
|---|---|---|
| miR-139-3p | miR-181c-3p | let-7e-5p |
| miR-182-5p | miR-181d-5p | miR-1224-5p |
| miR-182-5p_+_1 | miR-125a-5p | |
| miR-183-5p | miR-132-3p | |
| miR-183-5p_+_1 | miR-184-3p | |
| miR-328-3p | miR-375-3p | |
| miR-672-5p | miR-375-3p_-_1 | |
| miR-744-5p | miR-375-3p_+_1 | |
| miR-375-3p_+_2 | ||
| miR-7a-2-3p | ||
| miR-7b-5p | ||
| miR-7b-5p_+_1 | ||
| miR-92b-3p | ||
| miR-99b-5p |
Only miRNAs that have an average reads per million mapped to miRNAs (reads per million mapped to miRNAs) >100 in either Sox9-Low or Sox9-High and have <2-fold enrichment in Sox9-Sublow (transit-amplifying cells) and Sox9-Negative (enterocytes) are shown.
EEC, enteroendocrine cell; miRNA, microRNA; RNA-seq, RNA sequencing.