Table 2.
Small RNA-seq Analysis Showing Differentially Expressed miRNAs (Adjusted P < .05) in Mouse Enteroids Treated With LNA-7 (n = 6) Relative to LNA-scr (n = 5)
| miRNA | log2FoldChange | Adjusted P |
|---|---|---|
| mmu-mir-7a-1-5p | –7.109435038 | 4.64E-43 |
| mmu-mir-7a-2-5p | –7.103216777 | 5.31E-43 |
| mmu-let-7f-1-5p | –0.854266518 | 8.57E-14 |
| mmu-let-7f-2-5p | –0.862650621 | 1.58E-13 |
| mmu-mir-215-5p | –1.460451901 | 3.96E-10 |
| mmu-mir-148a-3p | 0.495197848 | 5.41E-05 |
| mmu-mir-215-5p_+_1 | –1.050094118 | 1.02E-04 |
| mmu-mir-192-5p_+_2 | 0.309404578 | 2.82E-04 |
| mmu-mir-98-5p | –0.509809453 | 4.18E-04 |
| mmu-let-7i-5p | –0.402567428 | .001535664 |
| mmu-mir-30d-5p | 0.317770352 | .004397959 |
| mmu-mir-26a-2-5p | 0.149129242 | .004685784 |
| mmu-mir-26a-1-5p | 0.149100629 | .004685784 |
| mmu-mir-203-3p_+_1 | 0.592648674 | .009726977 |
| mmu-mir-30e-3p | 0.276607739 | .010577384 |
| mmu-mir-192-5p_+_1 | 0.204704048 | .010887894 |
| mmu-mir-192-5p | 0.206058351 | .01488005 |
| mmu-let-7g-5p | –0.48204363 | .035030773 |
miRNA, microRNA; RNA-seq, RNA sequencing.