Table 4.
Results for genetic analyses
| Genetic Variant | Outcome | Contrast | B | SE | P | Beta |
|---|---|---|---|---|---|---|
| rs1360780 | Avoidance (intercepts) | AA vs. (AG or GG) | 1.221 | 1.326 | 0.357 | 0.053 |
| AG vs. (AA or GG) | −0.537 | 0.755 | 0.478 | −0.041 | ||
| GG vs. (AA or AG) | 0.141 | 0.756 | 0.852 | 0.011 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | 0.586 | 0.857 | 0.494 | 0.045 | |
| AG vs. (AA or GG) | 0.261 | 0.488 | 0.593 | 0.035 | ||
| GG vs. (AA or AG) | −0.449 | 0.488 | 0.357 | −0.060 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | 0.478 | 0.617 | 0.438 | 0.052 | |
| AG vs. (AA or GG) | −0.308 | 0.351 | 0.380 | −0.059 | ||
| GG vs. (AA or AG) | 0.153 | 0.352 | 0.663 | 0.029 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | 0.795 | 0.529 | 0.133 | 0.156 | |
| AG vs. (AA or GG) | 0.373 | 0.301 | 0.216 | 0.129 | ||
| GG vs. (AA or AG) | −0.631 | 0.300 | 0.036 * | −0.218 | ||
| rs3800373 | Avoidance (intercepts) | AA vs. (AC or CC) | −0.130 | 0.762 | 0.865 | −0.010 |
| AC vs. (AA or CC) | −0.557 | 0.765 | 0.467 | −0.042 | ||
| CC vs. (AA or AC) | 1.914 | 1.269 | 0.132 | 0.087 | ||
| Avoidance (slopes) | AA vs. (AC or CC) | −0.683 | 0.488 | 0.162 | −0.091 | |
| AC vs. (AA or CC) | 0.505 | 0.491 | 0.304 | 0.067 | ||
| CC vs. (AA or AC) | 0.530 | 0.818 | 0.517 | 0.043 | ||
| Anxiety (intercepts) | AA vs. (AC or CC) | −0.023 | 0.355 | 0.949 | −0.004 | |
| AC vs. (AA or CC) | −0.305 | 0.356 | 0.392 | −0.058 | ||
| CC vs. (AA or AC) | 0.907 | 0.591 | 0.125 | 0.104 | ||
| Anxiety (slopes) | AA vs. (AC or CC) | −0.585 | 0.303 | 0.053 | −0.206 | |
| AC vs. (AA or CC) | 0.209 | 0.306 | 0.494 | 0.073 | ||
| CC vs. (AA or AC) | 1.056 | 0.506 | 0.037 * | 0.222 | ||
| rs1799971 | Avoidance (intercepts) | AA vs. (AG or GG) | 1.619 | 0.822 | 0.049 * | 0.113 |
| AG vs. (AA or GG) | −1.422 | 0.848 | 0.094 | −0.096 | ||
| GG vs. (AA or AG) | −2.228 | 2.332 | 0.339 | −0.055 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | −0.776 | 0.537 | 0.148 | −0.094 | |
| AG vs. (AA or GG) | 0.786 | 0.553 | 0.156 | 0.092 | ||
| GG vs. (AA or AG) | 0.287 | 1.522 | 0.850 | 0.012 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | 0.656 | 0.383 | 0.087 | 0.114 | |
| AG vs. (AA or GG) | −0.566 | 0.395 | 0.152 | −0.096 | ||
| GG vs. (AA or AG) | −0.981 | 1.085 | 0.366 | −0.060 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | −0.479 | 0.330 | 0.146 | −0.151 | |
| AG vs. (AA or GG) | 0.366 | 0.340 | 0.282 | 0.111 | ||
| GG vs. (AA or AG) | 1.080 | 0.933 | 0.247 | 0.120 | ||
| rs1800497 | Avoidance (intercepts) | AA vs. (AG or GG) | 0.068 | 1.614 | 0.966 | 0.002 |
| AG vs. (AA or GG) | −0.055 | 0.788 | 0.945 | −0.004 | ||
| GG vs. (AA or AG) | 0.036 | 0.760 | 0.962 | 0.003 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | 0.888 | 1.063 | 0.403 | 0.055 | |
| AG vs. (AA or GG) | 0.248 | 0.519 | 0.633 | 0.031 | ||
| GG vs. (AA or AG) | −0.431 | 0.501 | 0.390 | −0.056 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | −0.117 | 0.755 | 0.877 | −0.010 | |
| AG vs. (AA or GG) | 0.312 | 0.368 | 0.396 | 0.057 | ||
| GG vs. (AA or AG) | −0.263 | 0.355 | 0.460 | −0.050 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | 0.144 | 0.654 | 0.826 | 0.023 | |
| AG vs. (AA or GG) | 0.247 | 0.319 | 0.439 | 0.079 | ||
| GG vs. (AA or AG) | −0.260 | 0.308 | 0.399 | −0.087 | ||
| rs2254298 | Avoidance (intercepts) | Continuous | −0.134 | 0.775 | 0.863 | −0.010 |
| Avoidance (slopes) | Continuous | −0.137 | 0.495 | 0.782 | −0.018 | |
| Anxiety (intercepts) | Continuous | 0.433 | 0.360 | 0.229 | 0.081 | |
| Anxiety (slopes) | Continuous | −0.187 | 0.308 | 0.545 | −0.061 | |
| rs53576 | Avoidance (intercepts) | Continuous | 0.840 | 0.572 | 0.142 | 0.085 |
| Avoidance (slopes) | Continuous | 0.311 | 0.377 | 0.410 | 0.053 | |
| Anxiety (intercepts) | Continuous | 0.400 | 0.268 | 0.135 | 0.101 | |
| Anxiety (slopes) | Continuous | 0.181 | 0.232 | 0.435 | 0.082 | |
| rs41423247 | Avoidance (intercepts) | CC vs. (CG or GG) | 0.298 | 1.274 | 0.815 | 0.013 |
| CG vs. (CC or GG) | −0.053 | 0.778 | 0.945 | −0.004 | ||
| GG vs. (CC or AG) | −0.055 | 0.758 | 0.942 | −0.004 | ||
| Avoidance (slopes) | CC vs. (CG or GG) | −0.262 | 0.827 | 0.752 | −0.021 | |
| CG vs. (CC or GG) | −0.358 | 0.505 | 0.478 | −0.046 | ||
| GG vs. (CC or AG) | 0.432 | 0.491 | 0.379 | 0.057 | ||
| Anxiety (intercepts) | CC vs. (CG or GG) | 0.391 | 0.592 | 0.509 | 0.045 | |
| CG vs. (CC or GG) | −0.209 | 0.361 | 0.562 | −0.039 | ||
| GG vs. (CC or AG) | 0.060 | 0.352 | 0.866 | 0.011 | ||
| Anxiety (slopes) | CC vs. (CG or GG) | 0.772 | 0.505 | 0.126 | 0.160 | |
| CG vs. (CC or GG) | −0.240 | 0.309 | 0.436 | −0.082 | ||
| GG vs. (CC or AG) | −0.046 | 0.301 | 0.879 | −0.016 | ||
| rs6190 | Avoidance (intercepts) | AG vs. GG | 0.679 | 2.221 | 0.760 | 0.018 |
| Avoidance (slopes) | AG vs. GG | −0.394 | 1.447 | 0.786 | −0.018 | |
| Anxiety (intercepts) | AG vs. GG | −1.342 | 1.031 | 0.193 | −0.087 | |
| Anxiety (slopes) | AG vs. GG | −0.011 | 0.888 | 0.990 | −0.001 | |
| rs6198 | Avoidance (intercepts) | AA vs. (AG or GG) | 0.358 | 0.825 | 0.665 | 0.025 |
| AG vs. (AA or GG) | −0.810 | 0.855 | 0.343 | −0.055 | ||
| GG vs. (AA or AG) | 2.631 | 2.120 | 0.215 | 0.072 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | −0.258 | 0.531 | 0.628 | −0.032 | |
| AG vs. (AA or GG) | −0.127 | 0.551 | 0.818 | −0.015 | ||
| GG vs. (AA or AG) | 2.499 | 1.362 | 0.067 | 0.120 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | 0.001 | 0.382 | 0.998 | 0.000 | |
| AG vs. (AA or GG) | 0.018 | 0.396 | 0.965 | 0.003 | ||
| GG vs. (AA or AG) | −0.114 | 0.983 | 0.907 | −0.008 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | 0.091 | 0.331 | 0.784 | 0.027 | |
| AG vs. (AA or GG) | −0.184 | 0.343 | 0.591 | −0.054 | ||
| GG vs. (AA or AG) | 0.533 | 0.851 | 0.531 | 0.063 | ||
| rs4680 | Avoidance (intercepts) | AA vs. (AG or GG) | 0.673 | 0.912 | 0.460 | 0.042 |
| AG vs. (AA or GG) | −1.086 | 0.752 | 0.149 | −0.083 | ||
| GG vs. (AA or AG) | 0.780 | 0.824 | 0.343 | 0.055 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | −0.001 | 0.590 | 0.998 | −0.000 | |
| AG vs. (AA or GG) | 0.280 | 0.487 | 0.566 | 0.038 | ||
| GG vs. (AA or AG) | −0.340 | 0.532 | 0.523 | −0.042 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | −0.078 | 0.423 | 0.853 | −0.012 | |
| AG vs. (AA or GG) | −0.450 | 0.349 | 0.197 | −0.087 | ||
| GG vs. (AA or AG) | 0.603 | 0.381 | 0.114 | 0.106 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | −0.298 | 0.365 | 0.415 | −0.085 | |
| AG vs. (AA or GG) | 0.480 | 0.301 | 0.111 | 0.167 | ||
| GG vs. (AA or AG) | −0.331 | 0.329 | 0.315 | −0.106 | ||
| rs5522 | Avoidance (intercepts) | AA vs. (AG or GG) | −0.045 | 0.919 | 0.961 | −0.003 |
| AG vs. (AA or GG) | 0.307 | 0.944 | 0.745 | 0.019 | ||
| GG vs. (AA or AG) | −2.816 | 3.117 | 0.366 | −0.052 | ||
| Avoidance (slopes) | AA vs. (AG or GG) | 0.678 | 0.596 | 0.256 | 0.074 | |
| AG vs. (AA or GG) | −0.333 | 0.613 | 0.587 | −0.036 | ||
| GG vs. (AA or AG) | −4.142 | 2.016 | 0.040* | −0.133 | ||
| Anxiety (intercepts) | AA vs. (AG or GG) | 0.143 | 0.427 | 0.737 | 0.023 | |
| AG vs. (AA or GG) | −0.007 | 0.439 | 0.988 | −0.001 | ||
| GG vs. (AA or AG) | −1.578 | 1.449 | 0.276 | −0.073 | ||
| Anxiety (slopes) | AA vs. (AG or GG) | −0.149 | 0.368 | 0.686 | −0.042 | |
| AG vs. (AA or GG) | 0.254 | 0.378 | 0.501 | 0.070 | ||
| GG vs. (AA or AG) | −1.059 | 1.248 | 0.396 | −0.088 | ||
| rs6295 | Avoidance (intercepts) | CC vs. (CG or GG) | 0.259 | 0.906 | 0.775 | 0.016 |
| CG vs. (CC or GG) | −0.121 | 0.758 | 0.873 | −0.009 | ||
| GG vs. (CC or AG) | −0.081 | 0.868 | 0.926 | −0.005 | ||
| Avoidance (slopes) | CC vs. (CG or GG) | −0.183 | 0.591 | 0.758 | −0.020 | |
| CG vs. (CC or GG) | 0.607 | 0.494 | 0.219 | 0.079 | ||
| GG vs. (CC or AG) | −0.628 | 0.566 | 0.267 | −0.071 | ||
| Anxiety (intercepts) | CC vs. (CG or GG) | −0.109 | 0.421 | 0.796 | −0.017 | |
| CG vs. (CC or GG) | 0.040 | 0.352 | 0.909 | 0.008 | ||
| GG vs. (CC or AG) | 0.047 | 0.404 | 0.907 | 0.008 | ||
| Anxiety (slopes) | CC vs. (CG or GG) | −0.641 | 0.362 | 0.077 | −0.184 | |
| CG vs. (CC or GG) | 0.533 | 0.303 | 0.079 | 0.180 | ||
| GG vs. (CC or AG) | −0.116 | 0.349 | 0.740 | −0.034 |
*
p < 0.05