Table 3.
Distribution of GSTM1 and GSTT1 Genotypes in OSCC Patients with Different Histopathologic Grades
| Genotypes | OSCC grade |
P value | |||
|---|---|---|---|---|---|
| Grade I |
Grade II |
Grade III |
|||
| N=21 |
N=20 |
N=9 |
|||
| n (%) | n (%) | n (%) | |||
| GSTM1 | + | 7 (33.3) | 10 (50) | 4 (44.4) | 0.55 |
| - | 14 (66.7) | 10 (50) | 5 (55.6) | ||
| GSTT1 | + | 16 (76.2) | 19 (95) | 3 (33.3) | 0.002* |
| - | 5 (23.8) | 1 (5) | 6 (66.7) | ||
| GSTM1& | TM (+), TT (+) | 6 (28.6) | 10 (50) | 1 (11.2) | |
| GSTT1 combinations | TM (+), TT (-) | 1 (4.8) | 0 (0) | 4 (44.4) | 0.01* |
| TM (-), TT (+) | 10 (47.6) | 9 (45) | 2 (22.2) | ||
| TM (-), TT (-) | 4 (19) | 1 (5) | 2 (22.2) | ||
*, Fisher's Exact Test