Table 2.
Top SNPs associated with WMHV.
| CHR | BP | SNP | MAF | Closest Gene | SNP Type | P |
|---|---|---|---|---|---|---|
| 17 | 13,392,543 | rs7220676 | C = 0.4229 | HS3ST3A1, MIR548H3 | intergenic | 2.96E-08 |
| 17 | 13,395,795 | rs9675262 | T = 0.4373 | HS3ST3A1, MIR548H3 | intergenic | 1.15E-07 |
| 3 | 36,796,647 | rs9820240 | A = 0.2145 | DCLK3 | intron | 2.23E-07 |
| 1 | 229,156,248 | rs10916409 | C = 0.4411 | ISCA1P2 | intergenic | 4.55E-06 |
| 11 | 85,707,054 | rs540422 | T = 0.3401 | PICALM | intron | 9.68E-06 |
Abbreviations: BP, base pair (variant position); CHR, chromosome; MAF, minor allele frequency; SNP, single nucleotide polymorphism; WMHV, white matter hyperintensity volume.