Table 1.
Baseline demographic and clinical characteristics of study sample.
| Variable | Total sample |
|---|---|
| Participants, n (%) | 37 (100) |
| Age, years, Mean (SD) | 39.5 (11.7) |
| Sex, M/F, n (%) | 18/19 (49/51) |
| Weight, kg, Mean (SD) | 80.8 (16.9) |
| Body mass index, kg/m2, Mean (SD) | 26.8 (4.7) |
| Length of current episode, years, Mean (SD) | 5.2 (5.7) |
| Major depressive episodes, Single/recurrent, n % | 19/18 (51/49) |
| Failed antidepressant trialsa, Mean (SD) | 3.4 (1.6) |
| Failed antidepressant augmentationsa, Mean (SD) | 3.0 (1.2) |
| ECT nonresponder in current episode, n (%) | 6 (16) |
| MADRS total score, Mean (SD) | 35.6 (3.8) |
| MADRS-SI score, Mean (SD) | 3.3 (1.2) |
| QIDS-SR total score, Mean (SD) | 18.3 (4.2) |
| Lifetime history of suicide attempt, n (%) | 9 (24) |
| Comorbid panic disorder, n (%) | 4 (11) |
| Comorbid agoraphobia, n (%) | 10 (27) |
| Comorbid social phobia, n (%) | 10 (27) |
| Comorbid obsessive compulsive disorder, n (%0 | 2 (5) |
| Comorbid alcohol dependence, n (% | 1 (3) |
| Comorbid generalized anxiety disorder, n (%) | 10 (27) |
ECT electroconvulsive therapy, F female, M male, MADRS Montgomery-Åsberg Depression Rating Scale [25], MADRS-SI Montgomery-Åsberg Depression Rating Scale suicide item, QIDS-SR Quick Inventory of Depressive Symptomatology-Self Report [28].
aNumber of failed antidepressant trials and augmentations during current episode according to the Antidepressant Treatment History Form [26]