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. 2020 Feb 14;11:885. doi: 10.1038/s41467-020-14728-9

Fig. 1. FPR2-Gi coupling and overall structure of the complex.

Fig. 1

a 35S-GTPγS binding assays using FPR2- and C5aR-expressing cell membranes and purified Gi heterotrimer with increasing concentrations of WKYMVm (WKY for short in all figures). n = 3, data are mean ± s.e.m. Source data are provided as a Source Data file. b 3D cryo-EM density map and overall structure of FPR2-Gi with WKYMVm and scFv16. Cholesterol molecules are shown as pink sticks. Cryo-EM map is colored according to different subunits. The density of WKYMVm is shown in the upper middle.