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MSC derived CCL2 is also required for angiogeneic response. Representative images of wound sections at d-10 post wounding, probed with CD31 antibody (green) and nuclei counter stained with DAPI (blue) scale bar, 50 μm. Vessels per high power field were quantified within the wound bed, white arrows indicate intact vessel lumens. MSC treated wounds had increased vessel density compared to both control and MSC-KO treated wounds (n ≥ 5 ns, not significant ***p < 0.001).
