Table 2.

Analytical figure of merit. The different matrices (water, duodenum, colon, liver, kidney, spleen and blood) were evaluated based on the quality parameters of the calibration (linearity, sensitivity, limit of detection (LOD), limit of quantification (LOQ), recovery). F-Test was carried out to compare the variance between water and matrix calibration sensitivities.

Matrix	Linearity (r²)	Sensitivity [cps (ng g−1)−1]	LOD [µg g−1] organ	LOQ [µg g−1] organ	F-Test*	Recovery [%]
water	0.9994	390.68	0.035	0.042	1	100
duodenum	0.9979	526.35	0.070	0.115	0.13	135
colon	0.9995	483.10	0.466	1.394	0.56	92
liver	0.9996	465.66	0.024	0.049	0.44	96
kidney	0.9997	568.27	0.032	0.082	0.16	122
spleen	0.9959	547.35	0.039	0.082	0.13	96
blood	0.9983	528.93	0.008	0.015	0.20	97

*F-Test: water/matrix; F ≥ 0.99 for using water calibration only.