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. 2020 Jan 8;133(3):935–950. doi: 10.1007/s00122-019-03517-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Circos plot illustrating key genomic and genic features of the ‘Synthetic W7984’ ‘super-contig’ (705 assembly scaffolds, totalling 3.47 Mb) spanning the wider Tsc2 locus, based on the ‘Chinese Spring’ region 2B: 14,040,000–30,500,000 bp. Tracks, from outside to inside: (1) the super-contig, with size indicated in Mb. (2) tick marks to illustrate start/end points between scaffolds, (3) loops to indicate sequence homology of genes based on 91-mers, (4) histogram of transposable element density, (5) histogram of gene density, (6) candidate genes, (7) tick marks indicating the named SNPs that delineate the boundaries of the most likely Tsc2 region: (a) regions kukric1481512 to kukric637481453 (full names Kukri_c148_1512 and Kukri_c63748_1453, respectively) represent a conservative Tsc2 interval, based on clear recombinations in the AM panel and encompassing the peak of the MAGIC QTL in this region, (b) region BS0007530351 (full name BS00075303_51, originating from the same RefSeqv1.1 gene model as BS00070050_51) to kukric637481453, which spans the peak of the MAGIC QTL and contains AM panel GWAS hits 1–6, 10 and 12