Table 1.
Preoperative characteristics according to the patient group.
| Parameters | Overall | Elderly (≥65 years) |
Non-elderly (<65 years) |
P-value |
|---|---|---|---|---|
| n = 179 | n = 38 | n = 141 | ||
| Clinical demographics | ||||
| Sex (female, n, %) | 49, 27.4 | 14, 36.8 | 35, 24.8 | 0.140 |
| Age (years) | 51.3 ± 16.6 | 74.2 ± 6.4 | 45.2 ± 12.6 | 0.001 |
| Body mass index (kg/m2) | 21.5 (19.1–24.6) | 22.7 (18.9–26.2) | 21.5 (19.2–23.7) | 0.174 |
| Hypertension (n, %) | 16, 8.9 | 5, 13.2 | 11, 7.8 | 0.304 |
| Diabetes mellitus (n, %) | 43, 24.0 | 11, 28.9 | 32, 22.7 | 0.423 |
| Liver cirrhosis (n, %) | 8, 4.5 | 0, 0 | 8, 5.7 | 0.133 |
| Creatinine (mg/Dl) | 1.1 (0.8–1.5) | 1.3 (1.0–2.3) | 1.0 (0.7–1.4) | 0.001 |
| eGFR (ml/min/1.73 m2) | 77.3 (46.8–116.8) | 49.2 (24.6–74.6) | 86.6 (55.9–126.7) | 0.001 |
| ESRD (n, %) | 16, 8.9 | 4, 10.5 | 12, 8.5 | 0.699 |
| IV drug abuser (n, %) | 7, 3.9 | 0, 0 | 7, 5.0 | 0.161 |
| Preoperative condition | ||||
| Critical status (n, %) | 31, 17.3 | 10, 26.3 | 21, 14.9 | 0.099 |
| Ventilator support (n, %) | 27, 15.1 | 9, 23.7 | 18, 12.8 | 0.095 |
| Inotropic support (n, %) | 12, 6.7 | 4, 10.5 | 8, 5.7 | 0.288 |
| ICU hospitalization (n, %) | 27, 15.1 | 8, 21.1 | 19, 13.5 | 0.247 |
| LVEF (%) | 65.4 ± 9.8 | 66.5 ± 10.6 | 65.1 ± 9.5 | 0.434 |
| LVEF <50% (n, %) | 12, 6.7 | 2, 5.3 | 10, 7.1 | 0.689 |
| EuroSCORE II (%) | 2.9 (1.8–6.1) | 6.6 (4.1–11.7) | 2.4 (1.8–4.1) | 0.001 |
| Antibiotics course before surgery (days) | 15.0 (6.0–28.0) | 14.5 (6.0–28.5) | 15.0 (6.0–27.5) | 0.712 |
| Hospital stay before surgery (days) | 20.0 (9.0–31.0) | 19.0 (9.8–31.5) | 20.0 (8.5–31.0) | 0.609 |
| Clinical presentation | ||||
| Fever (n, %) | 117, 65.4 | 25, 65.8 | 92, 65.2 | 0.950 |
| Malaise (n, %) | 7, 3.9 | 1, 2.6 | 6, 4.3 | 0.647 |
| Bacteraemia (n, %) | 126, 70.4 | 27, 71.1 | 99, 70.2 | 0.920 |
| Heart failure, NYHA-FC ≥ 3 (n, %) | 28, 15.6 | 6, 15.8 | 22, 15.6 | 0.978 |
| Septic emboli-related complications (n, %) | 69, 38.5 | 9, 23.7 | 60, 42.6 | 0.034 |
| Cerebral infarction (n, %) | 41, 22.9 | 7, 18.4 | 33, 24.1 | 0.459 |
| ICH (n, %) | 12, 6.7 | 0, 0 | 12, 8.5 | 0.063 |
| Cerebral mycotic aneurysm (n, %) | 8, 4.5 | 0, 0 | 8, 5.7 | 0.133 |
| Othersa (n, %) | 20, 11.2 | 2, 5.3 | 18, 12.8 | 0.193 |
| Recurrent thromboembolism (n, %) | 9, 5.0 | 1, 2.6 | 8, 5.7 | 0.446 |
aSplenic infarction in 12; renal infarction in 4; spinal abscess in 2; liver abscess in 1; and lower limbs ischemia in 1.
ESRD, end-stage renal disease; EuroSCORE, European System for Cardiac Operative Risk Evaluation; ICH, intracranial haemorrhage; ICU, intensive care unit; IV, intravenous; LVEF, left ventricular ejection fraction; NYHA-FC, New York heart association-functional classification.