Table 1.
Clinical and Demographic Features
| Case | Publication | Age | Sex | Site | Presenting symptom | Initial/preliminary diagnosis | Final diagnosis |
|---|---|---|---|---|---|---|---|
| 1 | Weinreb et al. [12] | 29 | M | Neck soft tissue | Horner syndrome | PD SCC | ALES |
| 2 | Cruz et al. [2], Eloy et al. [3] | 42 | F | Thyroid gland | Anterior cervical mass | Small cell thyroid CA | CEFTE |
| 3 | Kikuchi et al. [9] | 11 | F | Neck soft tissue | Neck mass | ALES | ALES |
| 4 | Eloy et al. [3] | 24 | M | Thyroid gland | Large thyroid nodule | PD thyroid CA | CEFTE |
| 5 | Lezcano et al. [10], Bishop et al. [8], Rooper et al. [16] | 56 | F | Parotid gland | Painless neck mass | Basal cell ACA | ALES |
| 6 | Bishop et al. [8] | 37 | F | Sinonasal tract | Nasal obstruction and epistaxis | PD SCC | ALES |
| 7 | Bishop et al. [8] | 21 | M | Sinonasal tract | Proptosis | ALES | ALES |
| 8 | Bishop et al. [8] | 7 | F | Orbital soft tissue | Proptosis | Myoepithelial CA | ALES |
| 9 | Bishop et al. [8], Rooper et al. [16] | 40 | F | Parotid gland | Painless neck mass | Basal cell adenoma | ALES |
| 10 | Bishop et al. [8] | 19 | M | Thyroid gland | Neck mass | ALES | ALES |
| 11 | Bishop et al. [8] | 36 | F | Thyroid gland | Goiter | ALES | ALES |
| 12 | Alexiev et al. [7] | 41 | M | Sinonasal tract | Orbital pain and swelling | NUT CA | ALES |
| 13 | Lilo et al. [11], Rooper et al. [16] | 72 | M | Parotid gland | Painful parotid mass | ALES | ALES |
| 14 | Ongkeko et al. [15] | 36 | M | Thyroid gland | Enlarging neck mass | PD thyroid CA | ALES |
| 15 | Rooper et al. [16] | 58 | M | Submandibular gland | Painless neck mass | PD CA | ALES |
| 16 | Rooper et al. [16] | 63 | F | Parotid gland | Rapidly growing parotid mass | PD CA with basaloid features | ALES |
| 17 | Rooper et al. [16] | 77 | M | Submandibular gland | Neck mass | PD CA with basaloid features | ALES |
| 18 | Rooper et al. [16] | 32 | F | Parotid gland | Neck swelling | High grade neuroendocrine CA | ALES |
| 19 | Rooper et al. [16] | 32 | M | Parotid gland | Painless facial mass | PD CA with basaloid features | ALES |
| 20 | Rooper et al. [16] | 41 | M | Parotid gland | Painless neck mass | PD CA with basaloid features | ALES |
| 21 | Rooper et al. [16] | 46 | M | Parotid gland | Rapidly growing tender mass | Merkel cell CA | ALES |
| 22 | Morlote et al. [14] | 20 | F | Thyroid gland | Non-painful left neck mass | ALES | ALES |
| 23 | Madhevan et al. [13] | 18 | M | Sinonasal tract | Nasal mass | Basaloid variant of SCC | ALES |
ACA adenocarcinoma, ALES Adamantinoma-like Ewing sarcoma, CA carcinoma, CEFTE carcinoma with Ewing family tumor elements, F female, M male, PD poorly differentiated, SCC squamous cell carcinoma