Table 1.
Baseline characteristics of patients.
Total patients (n = 47) | Non-NASH (n = 27) | NASH (n = 20) | p-value | |
---|---|---|---|---|
Age (years) | 51.0 ± 12.7 | 46.9 ± 12.7 | 56.6 ± 10.4 | 0.007 |
Male: Female | 16:31 | 11:16 | 5:15 | 0.477 |
Body mass index (kg/m2) | 28.3 ± 6.2 | 27.9 ± 7.7 | 28.7 ± 3.7 | 0.612 |
ALT (IU/L) | 80.2 ± 43.1 | 82.2 ± 53.0 | 81.0 ± 28.4 | 0.926 |
AST (IU/L) | 59.6 ± 26.5 | 55.8 ± 30.2 | 67.3 ± 18.8 | 0.134 |
ALP (IU/L) | 88.2 ± 21.3 | 90.7 ± 24.4 | 86.1 ± 17.9 | 0.474 |
GGT (IU/L) | 79.0 ± 61.1 | 95.0 ± 76.2 | 62.9 ± 30.9 | 0.059 |
Total bilirubin (mg/dL) | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.986 |
Total cholesterol (mg/dL) | 181.9 ± 36.4 | 190.1 ± 33.1 | 173.8 ± 40.0 | 0.133 |
Triglycerides (mg/dL) | 154.9 ± 65.3 | 168.2 ± 68.9 | 144.8 ± 59.1 | 0.224 |
HDL-cholesterol (mg/dL) | 43.5 ± 11.1 | 44.2 ± 11.1 | 42.8 ± 11.9 | 0.674 |
LDL-cholesterol (mg/dL) | 112.6 ± 33.2 | 118.0 ± 34.0 | 106.3 ± 33.5 | 0.247 |
Fasting glucose (mg/dL) | 117.0 ± 32.4 | 105.9 ± 16.3 | 133.7 ± 41.9 | 0.012 |
Albumin (g/dL) | 4.2 ± 0.6 | 4.1 ± 0.8 | 4.2 ± 0.3 | 0.692 |
Platelet count ( × 103/L) | 207.8 ± 54.1 | 228.0 ± 46.8 | 177.5 ± 49.9 | 0.001 |
Note. – ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT γ-glutamyltransferase, HDL high density lipoprotein, LDL low density lipoprotein.