Table 1.
Cre recombinase | TLR9 genotype | %Expected | %Born | %Survival 24 h postbirth | Mice analyzed |
β-actin-cre– | TLR9fsWT/+ | 50 | 44.4 | 100 | 16 |
β-actin-cre+ | TLR9fsWT/+ | 50 | 55.6 | 100 | 20 |
β-actin-cre– | TLR9fsTM/+ | 50 | 60.3 | 100 | 47 |
β-actin-cre+ | TLR9fsTM/+ | 50 | 39.7 | 0 | 31 |
Vav-cre– | TLR9fsTM/+ | 50 | 51.2 | 100 | 21 |
Vav-cre+ | TLR9fsTM/+ | 50 | 48.8 | 0 | 20 |