Fig. 4.

Disruptive and conservative modes of fMRI maturation in developmental and metabolic context. (A) MI was positively correlated with $\mathrm{\Delta }CT$ (1)—regions that had disruptive development (MI $<$ 0) had faster rates of cortical thickness (CT) shrinkage during adolescence. (B) MI was negatively correlated with a prior map of postnatal expansion of cortical surface area (28)—disruptive maturation was greater in regions that showed greatest expansion after birth. (C) MI was negatively correlated with a prior map of the glycolytic index, a measure of aerobic glycolysis (AG) (28), and (D) MI was negatively correlated with a prior map of brain regional expression of AG-related genes (29, 30).