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Results of the acute lethal test by a single oral administration in KM mice (n = 10).
| Sample | Se Content (mg/g) | LD50 # (mg/kg bw) | LD50 (Se) * (mg Se /kg bw) |
|---|---|---|---|
| Sodium selenite 1 | 456.7 | 19.2 (16.2–22.7) $ | 8.8 (7.4–10.4) ^ |
| CS/COS-M | -- | >20 × 103 | -- |
| SeNPs-CS/COS-M | 15.1 | 11.06 × 103 (6.28 × 103 –19.51 × 103) $ | 167 (94.9–294.5) ^ |
# LD50 = median lethal dose; * LD50 (Se) = LD50 × Se content. $ The LD50 of the 95% confidence interval. ^ The LD50(Se) of the 95% confidence interval. 1 Reference [11].
