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. 2020 Feb 14;94(5):e01881-19. doi: 10.1128/JVI.01881-19

TABLE 1.

Animal demographicsa

Animal PAI Initial
Rechallenge
Other infection, dpi
Statusb ZIKV inoculation strain Inoculation dose in PFU (s.c.) ZIKV inoculation strain, dpi Inoculation dose in PFU (s.c.)
C1 295022 NP ZIKV-MR766 104 ZIKV-FP, 70 104 SHIV, 347
ZIKV-PR, 858 104
C2 321142 NP ZIKV-FP 106 ZIKV-PR, 675 104 DENV3, 164
C3 598248 P ZIKV-FP 104 ZIKV-PR, 809 104 None
C4 610107 NP ZIKV-FP 106 ZIKV-FP, 70 104 SHIV, 326
ZIKV-PR, 837 104
C5 827577 P ZIKV-FP 104 ZIKV-PR, 858 104 None
a

Public animal identifiers (PAI) are used in studies on the Zika Open Research Portal (https://zika.labkey.com/project/OConnor/begin.view?). All animals were female. Animal C1 was previously infected with 104 PFU of ZIKV-MR766 and rechallenged with 104 PFU of ZIKV-FP 70 days after initial ZIKV infection (45). Animal C2 was previously infected with 106 PFU ZIKV-FP and Dengue virus 3 164 days prior to initial ZIKV infection (47). Animals C5 and C3 were previously infected with 104 PFU of ZIKV-FP during their first and late second/early third trimesters of pregnancy, respectively (46). Animal C4 was previously infected with 106 PFU of ZIKV-FP and rechallenged 70 days after initial infection with104 PFU of ZIKV-FP (44). All animals were rechallenged with 104 PFU of ZIKV-PR 675 to 858 days after initial infection. ZIKV-MR766, Zika virus/R.macaque- tc/UGA/1947/MR766-3329; ZIKV-FP, Zika virus/H.sapiens-tc/FRA/2013/FrenchPolynesia-01_v1c1; ZIKV-PR, Zika virus/H.sapiens-tc/PUR/2015/PRVABC59. dpi, days after initial ZIKV infection.

b

The pregnancy status at the time of initial infection: NP, nonpregnant; P, pregnant.