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. 2020 Feb 14;94(5):e01246-19. doi: 10.1128/JVI.01246-19

FIG 4.

FIG 4

Binding of MUC16-eluted IgG to SIV antigens. SIV antigen binding specificities of the different IgG fractions, input IgG, GuHCl-treated IgG, and MUC16-eluted IgG, are shown. Binding was assayed for gp140 SIVsmE660 (A), SIV gp140 (B), SIVmac251 gp130 (C), SIVmac239 gp120 (D), SIV gp41 (E), SIV p27 (F), and SIV p55 (G). IgG BAMA specific activity was calculated as the ratio of [blank and background-subtracted MFI (within the linear range of the BAMA) × dilution]/total IgG (micrograms per milliliter). Each point represents an individual macaque (n = 14 rhesus macaques). *, FDR-corrected P value of <0.05 by a sign test.