Human IL-6 is not a strong inducer of ITGB3 as is vIL-6 in HUVEC. (A) Immunoblots of total cell lysates from HUVEC expressing EV, vIL-6, or hIL-6 treated for 48 h in the presence of recombinant hIL-6 at the indicated concentrations. (B) Immunoblots of HUVEC treated with conditioned medium from EV-, vIL-6-, and hIL-6-expressing HUVEC and BJABs. (C) Similar to panel A, but EV- and vIL-6-HUVEC were grown for 24 h in the presence of recombinant hIL-6 (rhIL-6; 250 ng/ml), soluble IL-6Rα (sIL-6R; 250 ng/ml), or both.