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. 2020 Feb 14;94(5):e01644-19. doi: 10.1128/JVI.01644-19

TABLE 1.

Summary of animals, viruses, and virologic outcomes

Study Animal Challenge virus No. of
challenges
Age at first
exposure (wks)
Age at
infection
(wks)
Infection
duration
Age at
necropsy
(wks)
Peak viremia
(no. of
copies/ml)
Necropsy viremia
(no. of copies/ml)
1a 1A SIVmac251 2 12 14 13 25 89,000,000 16,000,000
1B SIVmac251 10 12 22 12 24 48,000,000 900,000
1C SIVmac251 2 12 14 13 25 230,000,000 200,000,000
1D SIVmac251 1 12 13 13 25 16,000,000 1,700,000
1E SIVmac251 1 12 13 12 24 16,000,000 7,400,000
2b 2A SHIV1157ipd3N4 18 12 30 6 18 210,000 4,600
2B SHIV1157ipd3N4 3 12 15 7 19 590,000 1,500
2C SHIV1157ipd3N4 3 12 14 8 20 26,000,000 910,000
2D SHIV1157ipd3N4 16 12 28 6 18 64,000,000 220,000
2E SHIV1157ipd3N4 1 12 12 7 19 33,000,000 58,000
2F SHIV1157ipd3N4 13 12 25 6 18 16,000 250
3 3A SHIV.C.CH505.375H.dCT 2 6 8 27 36 4,700,000 18,000
3B SHIV.C.CH505.375H.dCT 2 6 8 27 35 2,800,000 1,300
3C SHIV.C.CH505.375H.dCT 17 6 23 23 42 1,000,000 1,000,000
3D SHIV.C.CH505.375H.dCT 2 6 8 25 35 2,900,000 20
a

Data are from reference 44.

b

Data are from reference 49.