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. 2020 Jan 16;10(1):149. doi: 10.3390/biom10010149

Figure 1.

Figure 1

Effects of methamphetamine (MA) on mean arterial pressure (MAP), heart rate (HR), in conscious Sprague Dawley rats. Time-course in MAP (A) and HR (B) in rats 10 min before and 120 min after intraperitoneal (i.p.) injection of saline (n = 6), MA 2 mg/kg (n = 5), and MA 10 mg/kg (n = 8). Values are mean ± SEM, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 versus the corresponding time of the saline group or v p < 0.01, vv p < 0.0001 versus the corresponding time of the MA 2 mg group analyzed by two-way ANOVA measures followed by Bonferroni’s multiple comparison post-test.