Table 2.
Percentages of bound Sunitinib (SUT) and Semaxanib (SEM) by imprinted (MIP) and non-imprinted (NIP) particles and α and ε values for different Ci. Data are shown as means ± S.D.
| Ci (mol/L) | Bound SUT (%) | Bound SEM (%) | α SUT | α SEM | ɛ | ||
|---|---|---|---|---|---|---|---|
| MIP | NIP | MIP | NIP | ||||
| 0.00001 | 47.2 ± 0.6 | 34.5 ± 0.5 | 12.5 ± 0.6 | 11.5 ± 0.4 | 1.37 | 1.09 | 3.77 |
| 0.00002 | 51.5 ± 0.7 | 42.5 ± 0.7 | 14.1 ± 0.6 | 11.8 ± 0.7 | 1.21 | 1.19 | 3.66 |
| 0.00004 | 56.3 ± 0.4 | 40.3 ± 0.3 | 11.8 ± 0.5 | 10.1 ± 0.6 | 1.40 | 1.16 | 4.79 |
| 0.00006 | 58.3 ± 0.5 | 41.7 ± 0.5 | 7.9 ± 0.8 | 6.6 ± 0.4 | 1.40 | 1.20 | 7.37 |
| 0.00008 | 66.9 ± 0.6 | 46.3 ± 0.4 | 26.9 ± 0.4 | 22.5 ± 0.8 | 1.45 | 1.19 | 2.49 |
| 0.0001 | 71.0 ± 0.7 | 47.9 ± 0.6 | 42.1 ± 0.5 | 37.9 ± 0.5 | 1.48 | 1.11 | 1.69 |
| 0.0002 | 75.0 ± 0.4 | 48.3 ± 0.6 | 50.2 ± 0.7 | 47.3 ± 0.5 | 1.55 | 1.06 | 1.49 |
| 0.0004 | 80.3 ± 0.8 | 50.0 ± 0.3 | 52.8 ± 0.5 | 51.3 ± 0.7 | 1.61 | 1.03 | 1.52 |
| 0.0006 | 77.5 ± 0.5 | 47.5 ± 0.8 | 50.8 ± 0.6 | 48.3 ± 0.3 | 1.63 | 1.05 | 1.52 |
| 0.0008 | 68.8 ± 0.3 | 46.3 ± 0.5 | 42.5 ± 0.4 | 40.1 ± 0.7 | 1.49 | 1.06 | 1.62 |