Table 3.
Cytotoxicity of HAPs and HAP-Ps on the cell viability (%) of HCT116 spheroids.
| Concentration (µg/mL) | HAP | HAP-P |
|---|---|---|
| 48 h | ||
| 12 ** | 90.16 ±6.9 | 110.7 ±5.0 |
| 37 ** | 96.09 ±14.8 | 117.05 ±1.3 |
| 111 ** | 78.29 ±9.6 | 107.56 ± 12.0 |
| 333 ** | 88.18 ±6.4 | 91.74 ±7.0 |
| 1000 ** | 78.69 ±6.9 | 88.58 ±5.0 |
| 72 h | ||
| 12 | 129.2 ±12.7 | 129.2 ±9.7 |
| 37 | 122.1 ±17.2 | 122.1 ±19.0 |
| 111 | 130.8 ±15.6 | 130.8 ±14.0 |
| 333 | 125.7 ±11.4 | 125.7 ±11.6 |
| 1000 | 120.7 ±6.7 | 120.7 ±4.3 |
** Significant difference (p = 0.0049) between concentrations at 48 h. No significant difference was observed between HAP and HAP-P at 48 or 72 h.