Table 3.

Multivariable risk regression of predictive factors for adrenal insufficiency clustered by ACTH dose.

Factor	RR	95% CI	p-Value
Chronic kidney disease	2.52	2.02–3.14	<0.001
Cushingoid appearance in exogenous steroid and/or herbal medicine use	3.44	2.16–5.47	<0.001
Nausea and/or vomiting	1.84	1.24–2.75	0.003
Fatigue	1.23	1.11–1.37	<0.001
Serum basal cortisol < 9 µg/dL	3.36	3.23–3.49	<0.001
Cholesterol < 150 mg/dL	1.26	1.20–1.32	<0.001
Serum sodium < 135 mEq/L	1.09	1.04–1.15	0.001