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. 2020 Jan 2;9(1):37. doi: 10.3390/foods9010037

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of nutmeg essential oil ethanol solutions (a) and nutmeg essential oil hydrolats (b) on viability of cultured human fibroblasts. EO1—essential oil without excipient solution, EO2—essential oil with 1% magnesium aluminometasilicate solution, EOH1—hydrolat from EO1, and EOH2—hydrolat from EO2. In addition, 96% ethanol was assessed as solvent control for the essential oil. Punctured lines indicate the dilution ratios corresponding to LD₅₀. *—statistically significant difference compared to untreated control, #—compared to EO1 in (a) or EOH1 in (b), respectively, when p < 0.05.