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. 2020 Jan 8;9(1):54. doi: 10.3390/antiox9010054

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of KL5 and KL5E10 in the in vitro model of inflamed intestinal epithelium. (A) LPS-stimulated THP-1 cytokines release normalized to control (dashed line); (B) Caco-2 cell viability with different concentrations of the samples; (C) phenol red permeability assay; (D) effect of the samples on Caco-2 trans-epithelial electric resistance (TEER) in basal conditions; (E) effects of Kwht on Caco-2 TEER in inflammatory conditions; (F) effects of Ksgn on Caco-2 TEER in inflammatory conditions. * p < 0.05 vs. Ctrl; ** p < 0.01 vs. Ctrl; *** p < 0.001 vs. Ctrl; ° p < 0.05 vs. stimulus; °° p < 0.01 vs. stimulus; °°° p < 0.001 vs. stimulus.