Table 2.

ARE and AP1-binding sites within -5 kbp to TSS and to TIS of ER-stress gene promoters.

ID	Name	ARE/EpRE (5′-TGAC/GnnnGC-3′)	TRE/AP1 Site (5′-TGAC/GTCA-3′)
3309	BIP/GRP78	TGGCGCAATCTCAGCTC (–4344 to –4328) ATTTTGACCAGGCTGGT (–3811 to –3795) TGGTGCGATCTCAGCTC (–2848 to –2832) TAAGTGACTGTGCTTTG (–2480 to –2464) GAGCTGAGATTGCACTA (–1339 to –1323)	CTCTTGAGTCACCAG (–2104 to –2090) GTACTGAGTCACAGG (–2048 to –2034)
9451	PERK	GGTTTGAGTTCGCTCAT (–2728 to –2712) TCTAGCAAACTCATATA (–1844 to –1828) GCGTGCCAGGTCAGAGT (–719 to –703) CCAATGAGAGAGCAAAC (+60 to +76)
22926	ATF6	TCTTGCTCTGTCACCCA (–3459 to –3443) GAGCTGAGATGGCTCCA (–2054 to –2038) GTTCTGAGATAGCCACG (–343 to –327)
1649	Chop	CACAGCTTGGTCATGTC (–4521 to –4505) AAGGGCTACCTCAGTCA (–4384 to –4368) AGGCGCCCTGTCACCCA (–2780 to –2764) TCTCGCTCTGTCACCCA (–935 to –919) AAGCTGAGTTGGCCAGG (+2219 to +2235)	CGCATGACTCACCCA (–242 to –228)
2081	IRE1	ACCCGCCACCTCAGCCT (–4079 to –4063) TGAGTGACTTGGCCGTG (–692 to –676) AGTCTGACGCGGCAGGT (–370 to –354) TGAGGCTCGGTCACCGC (+26 to +42)
7494	XBP1	TCCCTGACCGAGCTGGT (–4419 to –4403) CACTGCAGCCTCAATCT (–4205 to –4189) CTCAGCCTCCTCAGTAG (–3987 to –3971) ATGTTGACCAGGCTGGT (–3901 to –3885) CTGTTGACCAGGCTGGA (–2943 to –2927) CTGGTGACAGAGCCTGA (–869 to –853) AAATGCACGCTCATAGT (–701 to –685)	GGCATGAGTCACCGT (–4306 to –4292)
468	ATF4	CTGCTGAGATTGCAGTA (–4933 to –4917) ATCTTGAGAGAGCTCAT (–4449 to –4433) ACCATGACTGGGCAAGC (–3612 to –3596) TTGCTGACTGTGCTCCC (–3105 to –3089) GGACTGACTTGGCTGAG (–2940 to –2924) ATTTGCACAGTCATCTG (–2230 to –2214) CCTCTGAGGCAGCAGGA (–1788 to –1773) CCATGCAGACTCAGCCG (–893 to –877)	GGCGTGAGTCAAGGG (+513 to +527)

Note: The red nucleotide letters represent the indicated consensus motifs. TSS and TIS denote the indicated transcriptional start signals and translation initiation signals deciphered in distinct genes, respectively.