Figure 2.

Light microscope observations of untreated human red blood cells [8,34,37,40,41] (A,D,G), or exposed to either pH 6.5 SO₄⁼ medium (B) or to pH 6.5 SO₄⁼ medium plus 10 μM curcumin [34] (C); human erythrocytes exposed to either 300 μM H₂O₂ (E), or exposed to 10–300 μM H₂O₂ (pre-conditioning) [37] (F) in SO₄⁼ medium incubation; human erythrocytes exposed to either 300 µM H₂O₂ (H), or exposed to 100 Melatonin plus 300 µM H₂O₂ [40] (I) in SO₄⁼ medium incubation. 400× magnification. Arrows indicate erythrocytes morphological alterations. Red blood cells shape is irregular due to spines, if compared to the untreated erythrocytes. Pictures are modified from references cited above.