Figure 1.

An overview of the genome-reduced E. coli strains. The strains are arranged from top to bottom according to decreasing genome size. The deletions responsible for the percentages in genome size reduction are indicated. The strain name, growth property and medium used are summarized within the boxes. The historical relations among the reduced genomes are connected by bold solid lines. The changes in growth rate are denoted with upward arrows, hyphens and downward arrows, which indicate increased, unchanged and decreased growth rates, respectively. The media used for the growth assay are indicated. The media (LB, MM, M9, M63, CSL medium and Antibiotic Medium 3) used for the growth assay are indicated. The compositions of the media are summarized in Table S2.