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. 2020 Jan 20;12(1):83. doi: 10.3390/pharmaceutics12010083

Figure 7.

Figure 7

PEI-coated MSNs as anti-osteoporotic nanocarrier. Osteostatin was loaded in the mesopores and a siRNA able to knockdown the SOST gene was introduced within the polymeric mesh. The co-delivery of both therapeutic agents resulted in synergistic osteogenesis in ovariectomized mice. PEI: polyethyleneimine.