Table 1.
Clinical features synopsis (review of literature).
| Year | Article | No. of Cases | Sex | Age | PD Duration | PD Clinical Signs | MG Time of Evolution | MG Clinical Signs |
|---|---|---|---|---|---|---|---|---|
| 1987 | Neurology 1987; 37 (5): 832–833; [6] | 1 | M | 55 | Five years | Tremor, hypomimia | Five years after PD | Diplopia, bilateral ptosis, muscle weakness of the neck and shoulder muscles |
| 1991 | Srp. Arh. Celok. Lek. 1991 Mar-Apr; 119 (3–4): 103–6; [7] | 1 | M | 77 | Three years | Tremor, axial rigidity | Bilateral ptosis, diplopia, dysphagia, dysarthria | |
| 1993 | Clin. Neurol. Neurosurg. 1993; 95 (2): 137–l39; [8] | 1 | F | 62 | Eight years | Tremor, hypomimia bradykinesia, Limb rigidity |
One year duration, Seven years after PD |
Fluctuating left eye ptosis, diplopia, dysphagia, generalized muscle weakness |
| 2003 | J. Neurol. 2003; 250: 766–767; [9] | 4 | 3 M; 1 F | 76; 62; 68; 61 |
||||
| 2008 | Parkinsonism Relat. Disord. 14 (2): 164–165; [10] | 1 | F | 58 | Five years | Right superior limb tremor, bradykinesia, rigidity | Six months | Head drop |
| 2009 | Movement Disorders, Vol. 24, No. 13, 2009, 2025–2026; [11] | 1 | M | 84 | Four years | Right superior limb tremor, bradykinesia, rigidity | Four years after PD | Head drop |
| 2011 | Neurologist 2011; 17 (3): 144–146; [12] | 1 | M | 75 | Eight years | Eight years after PD | Head drop | |
| 2014 | The Neurohospitalist. 2014, Vol. 4 (3): 117–118; [13] | 2 | 1 F; 1 M | 70; 72 |
1 two years; 2. one year after MG diagnosis |
Right superior limb tremor, bradykinesia, rigidity | 1.—generalized form; 2.—ocular form |
|
| 2014 | Neurol. Sci. 2014. 35 (5): 797–799; [14] | 1 | M | 69 | Five years | Left superior limb rigidity | Neck flexion weakness | |
| 2016 | Parkinsonism Relat. Disord. 2016; 28: 166–168; [15] | 3 | 1 F; 2 M |
67; 64; 72 |
1. ten years; 2. four years; 3. two years |
1.—asthenia, bilateral ptosis 2.—bilateral ptosis, head drop; 3.—asthenia, bilateral ptosis, diplopia |
||
| 2016 | J. Clin. Anesth. 2016; 34: 350–351; [16] | 1 | M | 68 | Two months | Bradykinesia, Dysarthria |
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| 2016 | Geriatr. Gerontol. Int. 2016; 16 (4): 528–530; [17] |
1 | F | 90 | Nine years | Hypomimia, bradykinesia, rigidity, dysarthria, rest tremor | Nine years after PD | Profound dysphagia |
| 2016 | J. Neurol. Disord. 2016, 4:4; [18] | 1 | M | 73 | 20 years | Hypertonic-akinetic syndrome | Diplopia, bilateral ptosis, dysphagia, muscle weakness of neck, trunk and limbs | |
| 2016 | J. Am. Geriatr. Soc. 2016; 64 (10): e120–e122; [19] | 1 | F | 76 | Five years | Akinesia and slight rigidity | Head drop | |
| 2017 | J. Neurol. Sci. 2017; 376: 216–218; [20] | 1 | M | 75 | Eight months | Hypomimia, Hypophonia, neck rigidity, shuffling gait, right limb bradykinesia | Diplopia, head drop | |
| 2018 | Nervenartz. 2018: 89 (4): 443–445; [21] | 4 | M | 82; 95; 83; 81 |
1.—six years; 2.—five years; 3.—five years 4.—seven years |
Progressive dysphagia in all four cases | ||
| 2019 | Clin. Neurol. Neurosurg. 2019. 179 1–3; [22] | 1 | M | 73 | Eight years | Bradykinesia, rigidity, left limbs rest tremor | Eight years after PD | Asthenia, dysphagia, diplopia |