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The death by a single oral administration of sustained-release TTX pellets on Sprague–Dawley (SD) rats in acute toxicity test.
| Dose (μg/kg) | ♀ | ♂ | Death |
|---|---|---|---|
| 1466 | 5/5 | 5/5 | 10/10 |
| 1100 | 3/5 | 2/5 | 5/10 |
| 825 | 3/5 | 1/5 | 4/10 |
| 618 | 3/5 | 2/5 | 5/10 |
| 464 | 0/5 | 0/5 | 0/10 |
| Total | 14/25 | 10/25 | 24/50 |
| LD50 | 771.65 | 927.98 | 840.13 |
