Table 4.
Pharmacokinetic parameters of TTX in rats after i.v. TTX injection administration at 6 μg/kg body wt. (n = 6, mean ± SD). Reproduced from Bihong Hong et al. [16], which is licensed under a Creative Commons Attribution-(CC BY 4.0) International License.
| Parameters | Unit | i.v. TTX of 6 μg/kg |
|---|---|---|
| AUC0–t | ng·h/mL | 4.42 ± 0.90 |
| AUC0–∞ | ng·h/mL | 4.63 ± 0.90 |
| t 1/2 | h | 0.92 ± 0.17 |
| CL 1 | mL/h/kg | 1349.40 ± 326.75 |
| V d 2 | mL/kg | 1824.68 ± 709.84 |
1 Total body clearance; 2 steady state apparent volume of distribution.