Table 4.
Proteins in the sarcoplasmic fraction demonstrating a potential aging effect.
| Protein Symbol | Protein Name | YT Mean ± SD | YU Mean ± SD | OU Mean ± SD |
|---|---|---|---|---|
| OU < other groups (p < 0.05) | ||||
| KRT9 | Keratin, type I cytoskeletal 9 | 430.4 ± 138.7 | 392.1 ± 24.9 | 250.6 ± 61.1 |
| FHL1 | Four and a half LIM domains protein 1 | 322.9 ± 70.9 | 278.1 ± 32.7 | 221.9 ± 32.8 |
| KRT2 | Keratin, type II cytoskeletal 2 | 202.9 ± 66.5 | 185.2 ± 41.3 | 133.0 ± 31.7 |
| DUSP3 | Dual specificity protein phosphatase 3 | 33.9 ± 11.6 | 25.3 ± 9.0 | 8.9 ± 6.9 |
| ANXA2 | Annexin A2 | 37.5 ± 21.7 | 34.3 ± 16.5 | 8.2 ± 6.7 |
| GSN | Gelsolin | 35.0 ± 20.6 | 43.7 ± 24.0 | 7.6 ± 8.6 |
| ACYP2 | Acylphosphatase-2 | 69.1 ± 18.9 | 43.2 ± 25.7 | 0.0 ± 0.0 |
| UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | 50.8 ± 29.0 | 25.7 ± 27.1 | 0.0 ± 0.0 |
| OU > other groups (p < 0.05) | ||||
| ACO2 | Aconitate hydratase, mitochondrial | 596.0 ± 60.1 | 601.9 ± 45.4 | 764.7 ± 141.5 |
| FABP3 | Fatty acid-binding protein, heart | 474.9 ± 78.3 | 488.9 ± 84.9 | 672.2 ± 127.6 |
| MDH1 | Malate dehydrogenase, cytoplasmic | 386.0 ± 44.5 | 385.7 ± 61.4 | 493.6 ± 48.0 |
| HADHA | Trifunctional enzyme subunit alpha | 266.0 ± 55.4 | 287.6 ± 110.4 | 458.9 ± 141.5 |
| ACADVL | Very long-chain specific acyl-CoA dehydrogenase | 214.6 ± 21.5 | 208.7 ± 60.7 | 379.2 ± 149.0 |
| HADH | Hydroxyacyl-coenzyme A dehydrogenase | 229.1 ± 35.1 | 228.1 ± 33.9 | 327.0 ± 69.4 |
| CKB | Creatine kinase B-type | 59.8 ± 28.7 | 69.8 ± 46.2 | 307.0 ± 157.2 |
| ETFA | Electron transfer flavoprotein subunit alpha | 108.5 ± 28.4 | 120.8 ± 24.2 | 194.2 ± 61.1 |
| ETFB | Electron transfer flavoprotein subunit beta | 74.6 ± 27.7 | 76.6 ± 28.4 | 145.9 ± 61.9 |
| ACOT1 | Acyl-coenzyme A thioesterase 1 | 94.9 ± 17.2 | 92.7 ± 29.2 | 140.1 ± 31.2 |
| COQ9 | Ubiquinone biosynthesis protein COQ9 | 86.1 ± 16.5 | 93.3 ± 22.4 | 127.8 ± 28.1 |
| ES1 homolog | ES1 protein homolog, mitochondrial | 55.0 ± 34.0 | 73.5 ± 31.1 | 127.3 ± 46.1 |
| HSPA9 | Stress-70 protein, mitochondrial | 61.3 ± 11.4 | 62.2 ± 27.1 | 116.7 ± 47.5 |
| CYCS | Cytochrome c | 9.3 ± 10.9 | 19.1 ± 14.9 | 59.8 ± 12.7 |
| GPT | Alanine aminotransferase 1 | 34.7 ± 9.5 | 30.5 ± 10.3 | 59.2 ± 14.9 |
| ALDH2 | Aldehyde dehydrogenase, mitochondrial | 23.5 ± 25.8 | 21.0 ± 20.6 | 56.8 ± 24.9 |
| CTSD | Cathepsin D | 11.4 ± 8.5 | 7.6 ± 8.4 | 53.9 ± 15.4 |
| ALDH5A1 | Succinate-semialdehyde dehydrogenase, mitochondrial | 24.3 ± 20.6 | 20.2 ± 15.9 | 53.3 ± 23.6 |
| AIFM1 | Apoptosis-inducing factor 1, mitochondrial | 13.2 ± 6.2 | 8.7 ± 8.9 | 45.7 ± 26.8 |
| NIPSNAP2 | Protein NipSnap homolog 2 | 15.0 ± 13.6 | 16.6 ± 16.8 | 42.8 ± 13.5 |
| FABP4 | Fatty acid-binding protein, adipocyte | 4.7 ± 5.3 | 16.0 ± 17.8 | 35.9 ± 5.9 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase, mitochondrial | 4.8 ± 6.5 | 6.2 ± 7.2 | 28.7 ± 22.2 |
| IMPA1 | Inositol monophosphatase 1 | 15.6 ± 8.5 | 11.3 ± 10.4 | 26.5 ± 4.3 |
| NDUFB6 | NADH dehydrogenase 1 beta subcomplex subunit 6 | 0.0 ± 0.0 | 0.0 ± 0.0 | 25.8 ± 24.4 |
| DCXR | L-xylulose reductase | 6.6 ± 7.2 | 4.7 ± 6.2 | 24.4 ± 15.3 |
| NDUFB11 | NADH dehydrogenase 1 beta subcomplex subunit 11 | 0.5 ± 1.3 | 0.0 ± 0.0 | 22.6 ± 20.5 |
| LRPPRC | Leucine-rich PPR motif-containing protein, mitochondrial | 0.0 ± 0.0 | 0.7 ± 1.8 | 13.3 ± 12.0 |
| DGLUCY | D-glutamate cyclase, mitochondrial | 1.0 ± 1.5 | 0.0 ± 0.0 | 12.6 ± 10.3 |
| DCN | Decorin | 3.3 ± 5.2 | 3.9 ± 3.7 | 11.0 ± 3.4 |
Legend: all data are presented as relative expression values (normalized to total spectra).